Methacholine Chloride FDA Link

A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)

Also Known As:

Methacholine; Provocholine; 2- (Acetyloxy)- N,N,N- trimethyl- 1- propanaminium Chloride; Acetyl-2-methylcholine Chloride; Acetyl-beta-methacholine Chloride; Acetyl-beta-methylcholine; Mecholine; Mecholyl; Provokit; Acetyl 2 methylcholine Chloride; Acetyl beta methacholine Chloride; Acetyl beta methylcholine; Chloride, Methacholine; 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride

Pharmalogical Action Categories:

Bronchoconstrictor Agents
Miotics
Muscarinic Agonists
Parasympathomimetics

Organic Chemicals: 133
- Amines: 4871
  - Quaternary Ammonium Compounds: 136
    - Trimethyl Ammonium Compounds: 1
      - Methacholine Compounds
        Methacholine Chloride: 3535
- Onium Compounds
  - Quaternary Ammonium Compounds: 136
    - Methacholine Compounds
      - Methacholine Chloride: 3535

S R Woskie Selected Research

S R Woskie Research Topics

Disease

Drug/Important Bio-Agent (IBA)